Studies on the physiological chemistry of the salivary glands. XLIX. Stability of parotin in aqueous solution.
نویسندگان
چکیده
The hypocalcemic activity("calcium activity"; Ito, 1960)of parotin was reported to be more unstable in acid aqueous solution than in alkaline solution, and its activity decreased when incubated in phosphate buffer of pH 7.6 at 40•Ž for 1 hr.(Ito and Mizutani, 1952b). The present experiments were undertaken to study the effect of heat, acid, and alkaline treatments on the biological as well as physicochemical properties of parotin in solution.
منابع مشابه
Studies on the salivary gland hormones labeled with I 131. 3. Effect of ligation of several blood vessels on the degradation and distribution of I 131-labeled parotin in vivo.
Previously it was reported that large localization of radioactivity was found in liver, kidney and spleen following the intravenous injection of I 131-labeled Parotin to rats(Tanaka and Ito,1958). And subsequently it was also observed that the rate of degradation of I 131-labeled Parotin in vivo was remarkably decreased by the simultaneous injection of intact Parotin with the labeled Parotin to...
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عنوان ژورنال:
- Endocrinologia japonica
دوره 7 شماره
صفحات -
تاریخ انتشار 1960